There are multiple running gags throughout The Weekenders:
- The constantly changing themes of the pizza place (one weekend it's Kosher Pizza, and another it's Pizzakaust).
- A reference to Lor's many brothers and Lor never being quite sure exactly how many there are.
- Tino's single mother serving foods of highly questionable origin (Such as kelp ravioli and spinach Jell-O cones).
- Daisy May Draggentowski's poor people skills.
- Carver's obsession with proving that he is not 'magic'.
- Whenever Mrs. Katsufrakis says something, Tish says what she means, and Mrs. Katsufrakis then says: "is what I say (That's what I said)." (e.g.: In the episode To Tish, Mrs. Katsufrakis says "I leave you to kitchen my cup." when she really meant "I leave you to kiss and make up.")
- One of the group members always summing things up and ends an episode with the statement "Later days".
- Tino's tendency to break out into immature rants whenever he sees something inappropriate.
- The kids' teacher, Mr. Hossinfeld, referring to something as "a kick in the pants".
- Lor's constant desperation to relieve herself.
- Christie and Candi's mischievous nature and scheming.
- Tino becoming glued to various objects, such as beach towels and trees.
- Carver's obsession with shoes & coolness.
- Lor's tendency to overhear and misinterpret conversations of others.
- Buffy's level-headed responses to even the craziest of situations.